Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
experimental study
Adequacy of study:
disregarded due to major methodological deficiencies
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: The data were based on secondary source (MSDS, ChemID, RTECS. Primary source (Industrial Hygiene and Toxicology, 2nd ed., Patty, F.A., ed., New York, John Wiley & Sons, Inc., 1958-63Vol. 2, Pg. 1882, 1963) could not be retrieved.

Data source

Referenceopen allclose all

Reference Type:
secondary source
Title:
Unnamed
Reference Type:
secondary source
Title:
No information
Author:
ChemID

Materials and methods

Test guideline
Qualifier:
no guideline followed
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Bis(2-butoxyethyl) adipate
EC Number:
205-466-0
EC Name:
Bis(2-butoxyethyl) adipate
Cas Number:
141-18-4
Molecular formula:
C18H34O6
IUPAC Name:
1,6-bis(2-butoxyethyl) hexanedioate

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Results and discussion

Effect levels
Dose descriptor:
LD50
Effect level:
600 mg/kg bw
Remarks on result:
other: intraperitoneal

Applicant's summary and conclusion

Conclusions:
LD50 after intraperitoneal administration in rats was 600 mg/kg bw.

Executive summary:

LD50 was reported to be 600 mg/kg bw after intraperitoneal administration in rats. This information was based on secondary source; no further information could be retrieved from primary sources.