Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 205-466-0 | CAS number: 141-18-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Manufacture
Manufacture
- Manufacture name:
- Manufacture of bis(2-butoxyethyl)adipate
Contributing activity / technique for the environmentopen allclose all
- Name of activity / technique:
- Manufacture of BDEA
- Environmental release category (ERC):
- ERC1: Manufacture of the substance
- Name of activity / technique:
- Bis(2-butoxyethyl)adipate is not classified for the environment, so an exposure assessment of the environment is not required.
According to the REACH Guidance on information requirements and chemical safety assessment, Part E (page 27/58), the assessment of "human via the environment" should be performed on a case by case basis for acutely toxic substances cat 1, 2 and 3 and strong sensitizers. Bis(2-butoxyethyl)adipate is classified as harmful by oral intake (Acute tox. cat 4) and is not a strong sensitizer. Consequently the assessment of man via the environment is not required. Moreover, the exposure of man via the environment is not a likely route of exposure because releases to the environment are minimal. The substance is manufactured in a closed process and formulated in a polymer film that is enclosed in safety glass. - Environmental release category (ERC):
- ERC1: Manufacture of the substance
Contributing activity / technique for workersopen allclose all
- Name of activity / technique:
- Manufacrure of DBEA
- Process category (PROC):
- PROC 2: Chemical production or refinery in closed continuous process with occasional controlled exposure or processes with equivalent containment conditions
- Name of activity / technique:
- Manufacrure of DBEA
- Process category (PROC):
- PROC 3: Manufacture or formulation in the chemical industry in closed batch processes with occasional controlled exposure or processes with equivalent containment conditions
- Name of activity / technique:
- Manufacrure of DBEA
- Process category (PROC):
- PROC 4: Chemical production where opportunity for exposure arises
- Name of activity / technique:
- Manufacrure of DBEA
- Process category (PROC):
- PROC 8a: Transfer of substance or mixture (charging and discharging) at non-dedicated facilities
- Name of activity / technique:
- Manufacrure of DBEA
- Process category (PROC):
- PROC 8b: Transfer of substance or mixture (charging and discharging) at dedicated facilities
- Name of activity / technique:
- Manufacrure of DBEA
- Process category (PROC):
- PROC 9: Transfer of substance or mixture into small containers (dedicated filling line, including weighing)
- Name of activity / technique:
- Manufacrure of DBEA
- Process category (PROC):
- PROC 15: Use as laboratory reagent
- Name of activity / technique:
- Synthesis of bis(2-butoxyethyl)adipate in closed system that is a combination of a continuous and a batch system; sampling on the reactor is via a closed loop system with damp retour
- Process category (PROC):
- PROC 2: Chemical production or refinery in closed continuous process with occasional controlled exposure or processes with equivalent containment conditions
- Name of activity / technique:
- Synthesis of bis(2-butoxyethyl)adipate in closed system that is a combination of a continuous and a batch system; sampling on the reactor is via a closed loop system with damp retour
- Process category (PROC):
- PROC 3: Manufacture or formulation in the chemical industry in closed batch processes with occasional controlled exposure or processes with equivalent containment conditions
- Name of activity / technique:
- Synthesis of bis(2-butoxyethyl)adipate in closed system that is a combination of a continuous and a batch system; sampling on the reactor is via a closed loop system with damp retour.
- Process category (PROC):
- PROC 4: Chemical production where opportunity for exposure arises
- Name of activity / technique:
- Charging/uncharging the equipment. The empty packages are collected for controlled disposal.
- Process category (PROC):
- PROC 8a: Transfer of substance or mixture (charging and discharging) at non-dedicated facilities
- Name of activity / technique:
- Maintenance and cleaning
- Process category (PROC):
- PROC 8b: Transfer of substance or mixture (charging and discharging) at dedicated facilities
- Name of activity / technique:
- Transfer of bis(2-butoxyethyl)adipate to small containers
- Process category (PROC):
- PROC 9: Transfer of substance or mixture into small containers (dedicated filling line, including weighing)
- Name of activity / technique:
- Quality control of the synthesised product
- Process category (PROC):
- PROC 15: Use as laboratory reagent
- Related assessment:
- use assessed in an own CSR
Contributing scenario for the environment (related to workers activities)
ContribScenWorkersRepopen allclose all
Contributing scenario for the workers
Conditions of use for workers
Product (article) characteristics
Amounts used (or contained in articles), frequency and duration of use/exposure
Technical and organisational conditions and measures
TechCondRepopen allclose all
Effectiveness
- Route affected:
- inhalation
Effectiveness
- Route affected:
- dermal
Conditions and measures related to personal protection, hygiene and health evaluation
PPERepopen allclose all
Other conditions affecting workers exposure
- Place of use:
- indoor
OtherCondRepopen allclose all
Exposure of workers
ExpEstopen allclose all
- Type of exposure:
- inhalation (internal) long-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers v3
- Type of exposure:
- inhalation (internal) short-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers v3
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers v3
- Type of exposure:
- inhalation (external) short-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers v3
- Type of exposure:
- dermal (internal) long-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers v3
- Type of exposure:
- dermal (external) long-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers v3
Contributing scenario for the workers
Conditions of use for workers
Product (article) characteristics
Amounts used (or contained in articles), frequency and duration of use/exposure
Technical and organisational conditions and measures
TechCondRepopen allclose all
Effectiveness
- Route affected:
- inhalation
Conditions and measures related to personal protection, hygiene and health evaluation
PPERepopen allclose all
Other conditions affecting workers exposure
- Place of use:
- indoor
OtherCondRepopen allclose all
Exposure of workers
ExpEstopen allclose all
- Type of exposure:
- inhalation (internal) long-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers v3
- Type of exposure:
- inhalation (internal) short-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers v3
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers v3
- Type of exposure:
- inhalation (external) short-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers v3
- Type of exposure:
- dermal (internal) long-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers v3
- Type of exposure:
- dermal (external) long-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers v3
Contributing scenario for the workers
Conditions of use for workers
Product (article) characteristics
Amounts used (or contained in articles), frequency and duration of use/exposure
Technical and organisational conditions and measures
TechCondRepopen allclose all
Conditions and measures related to personal protection, hygiene and health evaluation
PPERepopen allclose all
Other conditions affecting workers exposure
- Place of use:
- indoor
Other conditions of use
Exposure of workers
ExpEstopen allclose all
- Type of exposure:
- inhalation (internal) long-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers v3
- Type of exposure:
- inhalation (internal) short-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers v3
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers v3
- Type of exposure:
- inhalation (external) short-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers v3
- Type of exposure:
- dermal (internal) long-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- other: Riskofderm 2.1
- Type of exposure:
- dermal (external) long-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers v3
Contributing scenario for the workers
Conditions of use for workers
Product (article) characteristics
Amounts used (or contained in articles), frequency and duration of use/exposure
Technical and organisational conditions and measures
TechCondRepopen allclose all
Effectiveness
- Route affected:
- inhalation
Conditions and measures related to personal protection, hygiene and health evaluation
PPERepopen allclose all
Other conditions affecting workers exposure
- Place of use:
- indoor
OtherCondRepopen allclose all
Exposure of workers
ExpEstopen allclose all
- Type of exposure:
- inhalation (internal) long-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers v3
- Type of exposure:
- inhalation (internal) short-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers v3
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers v3
- Type of exposure:
- inhalation (external) short-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers v3
- Type of exposure:
- dermal (internal) long-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers v3
- Type of exposure:
- dermal (external) long-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers v3
Contributing scenario for the workers
Conditions of use for workers
Product (article) characteristics
Amounts used (or contained in articles), frequency and duration of use/exposure
Other conditions
Technical and organisational conditions and measures
TechCondRepopen allclose all
Effectiveness
- Route affected:
- inhalation
Conditions and measures related to personal protection, hygiene and health evaluation
PPERepopen allclose all
Other conditions affecting workers exposure
- Place of use:
- indoor
OtherCondRepopen allclose all
Exposure of workers
ExpEstopen allclose all
- Type of exposure:
- inhalation (internal) long-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers v3
- Type of exposure:
- inhalation (internal) short-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers v3
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers v3
- Type of exposure:
- inhalation (external) short-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers v3
- Type of exposure:
- dermal (internal) long-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers v3
- Type of exposure:
- dermal (external) long-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers v3
Contributing scenario for the workers
Conditions of use for workers
Product (article) characteristics
Amounts used (or contained in articles), frequency and duration of use/exposure
Technical and organisational conditions and measures
TechCondRepopen allclose all
Effectiveness
- Route affected:
- inhalation
Conditions and measures related to personal protection, hygiene and health evaluation
Effectiveness
- Route affected:
- dermal
Other conditions affecting workers exposure
- Place of use:
- indoor
Other conditions of use
Exposure of workers
ExpEstopen allclose all
- Type of exposure:
- inhalation (internal) long-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers v3
- Type of exposure:
- inhalation (internal) short-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers v3
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers v3
- Type of exposure:
- inhalation (external) short-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers v3
- Type of exposure:
- dermal (internal) long-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers v3
- Type of exposure:
- dermal (external) long-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers v3
Contributing scenario for the workers
Conditions of use for workers
Product (article) characteristics
Amounts used (or contained in articles), frequency and duration of use/exposure
Technical and organisational conditions and measures
Technical and organisational conditions
Conditions and measures related to personal protection, hygiene and health evaluation
PPERepopen allclose all
Other conditions affecting workers exposure
- Place of use:
- indoor
Other conditions of use
Exposure of workers
ExpEstopen allclose all
- Type of exposure:
- inhalation (internal) long-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers v3
- Type of exposure:
- inhalation (internal) short-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers v3
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers v3
- Type of exposure:
- inhalation (external) short-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers v3
- Type of exposure:
- dermal (internal) long-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers v3
- Type of exposure:
- dermal (external) long-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers v3
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.