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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Link to relevant study record(s)

Description of key information

The Klimisch 1 study by Bouwman (2004) performed at NOTOX is considered the key study. This algal growth inhibition test with the unicellular green alga Selenastrum capricornutum (Pseudokirchneriella subcapitata), performed according to ISO Guideline 8692, EU Method C.3 and OECD Guideline 201,  yielded a 72-h NOEC and EC50 (based on growth rate reduction) of 4.6 and > 100 mg/L, respectively. These values can be used as key values for PNEC derivation.

Key value for chemical safety assessment

EC10, LC10 or NOEC for freshwater algae:
4.6 mg/L

Additional information

A single algal growth inhibition study is available (Bouwman, 2004). Under the conditions of this study with the unicellular freshwater green alga Selenastrum capricornutum (Pseudokirchneriella subcapitata), the substance reduced algal growth rate as well as biomass significantly at nominally 10 mg/L and higher. The 72-h NOEC, LOEC, EC10 and EC50 based on algal biomass were 4.6, 10, 4.4 and 44 mg/L, respectively, whereas the 72-h NOEC, LOEC, EC10 and EC50 based on algal growth rate were 4.6, 10, 20 and > 100 mg/L, respectively. The results of this test are valid and the study is considered a Klimisch 1 study.