Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 444-960-2 | CAS number: 39148-16-8
Endpoint summary
Administrative data
Description of key information
Additional information
One GLP study is available investigating the short-term toxicity of Fosetyl-Sodium to soil macroorganisms (OECD 207). The study was conducted with Eisenia fetida. Since no mortality occurred, the study resulted in a LC50 (14d) > 1000 mg/kg soil dw.
Furthermore, a GLP study according to the Guidelines for Testing of Chemicals (HJ/T 153-2004), China, was performed to assess the toxicity of Fosetyl-Sodium to seedlings (seed germination and root elongation test) of 10 crop species using quartz sand: green cabbage (Brassica chinensis L.), lettuce (Lactuca sativa), rice (Oryza sativa L.), wild cabbage (Brassica oleracea), cucumber (Cucumis sativus), corn (Zea mays), sesame (Sesamum indicum), tomato (Lycopersicon esculentum), soybean (Glycine max), and radish (Raphanus sativus). In order to estimate apropriate test concentrations, a pre-test was conducted with the following test concentrations: 100, 500, 1000 mg/L, and a negative control. The test was ended when germination rate for each seed type in the blank control group reached 65% or higher and root length exceeded 20 mm. Analytical measurements showed that concentrations were within +/- 20% of nominal concentrations and results were based on nominal values. The test results indicated that the test substance did not have a significant inhibitory effect (P > 0.05) on the seed germination and root elongation of the 10 terrestrial plant species in any of the tested concentrations. Therefore, the study was finished after the pre-test. The time for each seed type to reach a germination rate of 65% or higher and a root length exceeding 20 mm was 7 days. Therefore, the 7-day EC50 and NOEC for germination and root elongation in all tested plant species were > 1000 mg/L and ≥ 1000 mg/L, nominal, respectively.
The results of tests conducted with Fosetyl-Sodium are summerised in the following table:
Test species |
Test system |
Test duration (d) |
Endpoint |
Result |
Earthworm |
Short-term, artificial soil |
14 |
LC50 |
> 1000 mg/kg dw soil |
Brassica chinensis L., Lactuca sativa, Oryza sativa L., Brassica oleracea, Cucumis sativus, Zea mays, Sesamum indicum, Lycopersicon esculentum, Glycine max, Raphanus sativus |
Short-term, seed germination and root elongation |
7 |
EC50 NOEC |
> 1000 mg/L ≥ 1000 mg/L |
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
