Registration Dossier
Registration Dossier
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EC number: 444-960-2 | CAS number: 39148-16-8
Endpoint summary
Administrative data
Description of key information
Additional information
In regard of the stability of the test item in the environment only data on the hydrolysis are data requirements. Because no study on the hydrolysis is available for the target substance Fosetyl-Sodium (CAS 39148-16-8), this endpoint is covered by read-across to the analogous substance Fosetyl-Aluminium (CAS 39148-24-8).
The source substance Fosetyl-Aluminium is a long and widely used fungicide. The evaluation of the extensive data base available shows that Fosetyl-Aluminium is of very low acute and chronic toxicity. The target substance is a pre-manufacturing product for the synthesis of Fosetyl-Aluminium.
A GLP study according to OECD guideline 111 on the hydrolysis has been carried out with Fosetyl-Aluminium to determine the rate of hydrolysis in aqueous solutions at pH values normally found in the environment (pH 4, 7, and 9). A preliminary hydrolysis test was performed for 5 days at 50 °C in aqueous solutions at pH 4, 7, and 9. Under the conditions of the test no hydrolysis of Fosetyl-Al was detected. Fosetyl-Al is therefore considered to be hydrolytically stable. On the basis of the results from the preliminary test, no further work was conducted.
Based on the results with the source substance Fosetyl-Aluminium (CAS 39148-24-8), the target substance Fosetyl-Sodium (CAS 39148-16-8) is also considered to be hydrolytically stable.
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