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EC number: 244-168-5
CAS number: 21041-95-2
The frequency of micronuclei in peripheral blood erythrocytes of
mice following treatment with CdO by inhalation for 13 weeks, are given
The results are tabulated as the mean of the pooled results from
all animals within a treatment group, plus or minus the standard error
of the mean.
Micronucleated NCEs/1000 NCEs (mean ± standard error)
2.8 ± 0.3
3.7 ± 0.6
3.1 ± 0.9
3.1 ± 0.4
4.3 ± 0.6
2.1 ± 0.2
2.1 ± 0.4
2.2 ± 0.3
2.1 ± 0.3
2.7 ± 0.4
2.7 ± 0.3
Dunnick (1995) treated male and female B6C3F1 mice with cadmium oxide
(0.025, 0.05, 0.1, 0.25, 1 mg/m³) for 13 week to determine the frequency
of micronucleated erythrocytes in peripheral blood of these animals..
At the end of the 13-week study, smears were prepared and slides were
scanned to determine the frequency of micronuclei in 2,000
normochromatic erythrocytes in each of five male and five female mice
per exposure concentration
Inhalation exposure to cadmium oxide (0.025-1 mg/m3) for 13 weeks did
not result in increased frequencies in micronucleated erythrocytes in
peripheral blood of male or female B6C3F1 mice.
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