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EC number: 282-104-8 | CAS number: 84100-23-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
In an alga, growth inhibition test according to OECD guideline 201, recalculated EC50 - and EC10 -values for inhibition of specific growth rate after 72 h were 0.539 mg/L and 0.414 mg/L (based in time weighted average mean measured concentrations; BASF, 60E0580/09X174, 2015)
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 0.539 mg/L
- EC10 or NOEC for freshwater algae:
- 0.414 mg/L
Additional information
An algae growth inhibition test with the
freshwater green algae Pseudokirchneriella subcapitata was conducted
according to OECD guideline 201 (BASF, 60E0580/09X174, 2015). The aim of
the study was to assess the effects on the growth rate over a period of
72 hours. The study was conducted under static conditions with an
initial cell density of 6153 x 10^3 cells/ mL. The green algae were
exposed to the nominal test concentrations of 1, 3.16, 10, 31.6 and 100
mg test item/L, corresponding to the time weighted average mean measured
concentrations of 0.428, 1.32, 2.85, 3.49 and 3.89 mg/L.
All test concentrations of the test substance and the control were
analytically verified by GC-MS of the two diastereomers after 24 hours
and at the end of the exposure. The measured concentrations of the test
substance at the start of the exposure were in the range of 3 to 34 % of
the nominal test item concentrations. After 24 hours, 4 to 41 % of the
nominal test item concentration were found. At the end of the exposure 4
to 55 % of the nominal test item concentration were measured. In all
loadings the measured concentration increased during the exposure time.
It is assumed that at the beginning of the test the test item was not
completely dissolved.
The original report states EC50 - and EC10 -values for inhibition of specific growth rate of 0.690 mg/L and <0.428 mg/L after 72 h of exposure
(based on time weighted average mean measured concentrations). As a "lower than"-value for an EC10 is not appropriate in a regulatory context, a recalculation based on the raw data given in the report (measured cell densities) was performed. This re-evaluation using the statistical software ToxRatPro Version 2.10 resulted in values for ErC50 and ErC10 of 0.539 mg/L and 0.414 mg/L, respectively. These values are used in the further assessment of the registration item.
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