Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 282-104-8 | CAS number: 84100-23-2
Water solubility
Administrative data
Link to relevant study record(s)
Description of key information
The water solubility of the substance is determined to be 5 mg/L at 20 °C and pH = 6.1 - 6.3.
Key value for chemical safety assessment
- Water solubility:
- 5 mg/L
- at the temperature of:
- 20 °C
Additional information
A GLP study was conducted (BASF, 09L00334, 2009) according to OECD 105 and Regulation (EC) 440/2008 Part A to determine the water solubility of the test item. A preliminary test was conducted to estimate the water solubility of the test item. Therefore mixtures of the test item were prepared at different concentrations. After shaking or stirring for three days at room temperature the preparation were visually checked. The water solubility was estimated to be below 8 mg/L. Thus the determination according column elution method was chosen for main test. The determination was performed in duplicated. The samples were analysed via headspace gas chromatography with flame ionisation detector. The water solubility was determined to be 4.8 ± 0.7 mg/L at pH 6.1 to 6.4. No observations were made which cause doubt on the validity of the study.
In a non-GLP supporting study (BASF, OG 82-86, 1981) similar to Regulation (EC) 440/2008 Part A, A.8 the water solubility of the test item was determined using the shake flask method. A test item solution 10% (m/m) in water was prepared and stirred for 30 min. After 30 min settling time the aqueous phase was centrifuged. One part of the aqueous phase was mixed with dioxan in a ratio 1:1. The test item concentration was determined by gas chromatography. Two components of the test item were identified. The water solubility of component A was determined to be 60.75 mg/L and of component B 78.5 mg/L at 20 °C.
In conclusion the water solubility, as determined in the GLP and guideline study, was regarded as most reliable and therefore 5 mg/L was chosen as key value for chemical safety assessment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
