Registration Dossier

Administrative data

Endpoint:
dissociation constant
Type of information:
experimental study
Adequacy of study:
key study
Study period:
17.01.2013 - 31.01.2013
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2012
Report Date:
2013

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other:
Principles of method if other than guideline:
Measurement of capacity of a compound to dissociate into respective ions.
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
other: Amorphous
Details on test material:
- Name of test material : 3-amino-2hydroxy-5-nitrobenzenesulphonic acid
- Substance type: Organic
- Physical state: Solid

Results and discussion

Dissociating properties:
yes
Dissosciation constantopen allclose all
No.:
#1
pKa:
0.002
Temp.:
22 °C
No.:
#2
pKa:
0.002
Temp.:
22 °C
No.:
#3
pKa:
0.002
Temp.:
22 °C

Applicant's summary and conclusion

Conclusions:
The experimental pKa value for 3-amino-2-hydroxy-5-nitrobenzenesulphonic acid was found to be 0.00228 (average pKa value) at 22 deg C indicating that the chemical has dissociation properties.
Executive summary:

The experimental pKa value for 3-amino-2-hydroxy-5-nitrobenzenesulphonic acid was found to be 0.00228 (average pKa value) at 22 deg C indicating that the chemical has dissociation properties.