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EC number: 617-116-8
CAS number: 80573-04-2
Due to the apparent effect on the maintenance of pregnancy in females
receiving 600 mg/kg bw/day and above, the sponsor repeared part of the
experiment. In this repeat test three groups were included in which
pregnant rabbits were given oral doses of 0 (vehicle), 300 and 600 mg/kg
from day 6 to 19 of gestation. This experiment had a few problems, such
as older rabbits were used and were not in an active growth phase (even
control rabbits lost their weights during the gestation period). Hence,
no conclusion could be made from this study.
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