Registration Dossier

Physical & Chemical properties

Melting point / freezing point

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
11 July - 20 July 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
thermal analysis
Specific details on test material used for the study:
- Test material: Balsalazide acid
- Batch number: 0400
- Expiry date: April 2019
- Storage: Room temperature
Key result
Melting / freezing pt.:
276.4 °C
Decomposition:
yes
Decomp. temp.:
270.6 °C

Balsalazide acid underwent an endothermic reaction showing a melting transition of the test item followed by an exothermic degradation (Onset: 270.6°C).

Conclusions:
The melting point of Balsalazide acid was determined to be 276.4°C followed by an exothermic degradation.

Description of key information

The melting point of the test item, Balsalazide acid was determined according to OECD Guideline 102 and EC Method A.1 and was found to be 276.4°C, followed by an exothermic degradation.

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:
276.4 °C

Additional information