Registration Dossier
Registration Dossier
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EC number: 801-282-5 | CAS number: 1034343-98-0
Endpoint summary
Administrative data
Description of key information
The toxicity of the test item graphene towards soil organisms was assessed in a static test according to OECD TG 207 under GLP: Eisenia fetida LC50 (14d) > 1001 mg/kg soil dw
Additional information
The acute toxicity of the test substance to Eisenia fetida was determined in a 14 days artificial soil test according to "Ministry of environmental protection of the people's Republic of China, The Guidelines for the Testing of Chemicals-Effects on Biotic Systems, 2013, 207 Earthworm, Acute Toxicity Test" and "OECD, Guidelines for the Testing of Chemicals, 1984, 207 Earthworm, Acute Toxicity Test", in compliance with GLP.
Based on the results of a range-finding test, a limit test with a concentration of 1001 mg/kg dry artificial soil weight was conducted. 1 treatment groups and one control group, each consisting of four replicates of 10 worms per concentration were included in the main test. The numbers of mortalities were determined after 7 and 14 days exposure.
The mortalities of the earthworms in the blank control group and solvent control group were 0%, which was not more than 10 percent, i.e. the test is evaluated as valid.
Under the test conditions, the result for the 14 d median lethal concentration (LC50) was greater than 1001 mg/kg (dry weight of artificial soil).
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