Registration Dossier
Registration Dossier
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EC number: 201-969-4 | CAS number: 90-15-3
Long-term toxicity to fish
Administrative data
- Endpoint:
- long-term toxicity to fish, other
- Remarks:
- calculation
- Type of information:
- calculation (if not (Q)SAR)
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model, but not (completely) falling into its applicability domain, and documentation / justification is limited
- Remarks:
- ECOSAR predicts a higher value for chronic fish than the experimental test data available from acute fish studies (0.58 vs 0.33 mg/L, respectively)
Data source
Reference
- Reference Type:
- other: calculation
- Title:
- ECOSAR v1.11
- Author:
- EPA
- Year:
- 2 017
- Bibliographic source:
- ECOSAR (Ecological Structure-Activity Relationship) Class Program for Microsoft Windows v.1.11 (24 July 2012). U.S. Environmental Protection Agency. Office of Chemical Safety and Pollution Prevention.
Materials and methods
- Principles of method if other than guideline:
- calculation
Test material
- Reference substance name:
- 1-naphthol
- EC Number:
- 201-969-4
- EC Name:
- 1-naphthol
- Cas Number:
- 90-15-3
- Molecular formula:
- C10H8O
- IUPAC Name:
- naphthalen-1-ol
- Test material form:
- solid
Constituent 1
Results and discussion
Effect concentrations
- Duration:
- 36 d
- Dose descriptor:
- other: ChV
- Effect conc.:
- 0.838 mg/L
- Remarks on result:
- other: ECOSAR v1.11 calculation, Phenols class
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not applicable
- Conclusions:
- The calculated (ECOSAR v1.11, Phenols class) ChV (36d) is 0.838 mg/L. ECOSAR predicts a higher value for chronic fish than the experimental test data available from acute fish studies (0.58 vs 0.33 mg/L, respectively)
- Executive summary:
The calculated (ECOSAR v1.11, Phenols class) ChV (36d) is 0.838 mg/L. ECOSAR predicts a higher value for chronic fish than the experimental test data available from acute fish studies (0.58 vs 0.33 mg/L, respectively)
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