1-naphthol

Surface tension

Link to relevant study record(s)

Reference

Endpoint:

surface tension

Type of information:

experimental study

Adequacy of study:

key study

Study period:

From 27 May 2016 to 23 September 2016

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 115 (Surface Tension of Aqueous Solutions)

Deviations:

no

GLP compliance:

yes

Type of method:

ring method

Specific details on test material used for the study:

SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: A017 / Lot Number ADT1214003
- Expiration date of the lot/batch: TBD
- Purity test date: 27 May 2016
Re-analysis date : 08 June 2016 and Purity : 98.9%
Re-analysis date : 08 September 2016 and Purity : 99.2%
The purity is unchanged and remains 98.9%

STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: room temperature
- Stability under test conditions: yes
- Solubility and stability of the test substance in the solvent/vehicle: yes
- Reactivity of the test substance with the solvent/vehicle of the cell culture medium: no

TREATMENT OF TEST MATERIAL PRIOR TO TESTING
- Treatment of test material prior to testing: no
- Preliminary purification step (if any): no
- Final dilution of a dissolved solid, stock liquid or gel:
A test substance stock solution was prepared on 25 august 2016 by weighing 201.0 mg of the test substance into a 200-mL volumetric flask. The flask was then brought to volume with distilled water and sonicated to mix.
- Final preparation of a solid: no

FORM AS APPLIED IN THE TEST (if different from that of starting material)
Solid dissolved in distilled water

Key result

Surface tension:

ca. 60.1 other: dynes/cm

Temp.:

20.3 °C

Conc.:

1.005 g/L

Remarks on result:

other: 60.1 ± 0.82 dynes/cm at 20.3 ± 0.1 ºC

The temperature during the definitive test ranged from 20.2 to 20.4°C. The true surface tension of the test substance was determined to be 60.1 ± 0.82 dynes/cm at a temperature of 20.3 ± 0.1 ºC. Reproducibility was demonstrated as evidenced by the coefficient of variance (CV), which was 1.36%. The results are presented in the following table:

Sample	Elapsed Time (min)	Apparent Surface Tension (dynes/cm)	Calibration correction Factor	Instrument correction Factor	True Surface Tension (dynes/cm)
Replicate 1	4	67.8	0.971	0.928	61.1
	7	66.9	0.971	0.927	60.2
	10	66.8	0.971	0.927	60.1
Replicate 2	5	65.5	0.971	0.926	58.9
	8	65.3	0.971	0.925	58.7
	11	66.5	0.971	0.927	59.9
Replicate 3	5	68.4	0.971	0.928	61.6
	7	67.1	0.971	0.927	60.4
	10	66.9	0.971	0.927	60.2

Overal Mean : 60.1 ± 0.82

Percent CV 1.36

Conclusions:

The true surface tension of the A017 solution was determined to be 60.1 ± 0.82 dynes/cm at a temperature of 20.3 ± 0.1 ºC.

Executive summary:

The surface tension of A017 was determined according to the OECD 115 guideline and the GLP.

The Surface tension was measured with a Fisher Scientific Surface Tensiomat Model 21.

The true surface tension of the A017 solution at the concentration of 1.005 g/L was determined to be 60.1 ± 0.82 dynes/cm at a temperature of 20.3 ± 0.1 ºC.

Description of key information

The true surface tension of the A017 solution was determined to be 60.1 ± 0.82 dynes/cm at a temperature of 20.3 ± 0.1 ºC.

Key value for chemical safety assessment

Surface tension:

60.1

in mN/m at 20°C and concentration in mg/L:

1 005

Additional information

The surface tension of A017 was determined according to the OECD 115 guideline and the GLP.

The Surface tension was measured with a Fisher Scientific Surface Tensiomat Model 21.

The true surface tension of the A017 solution at the concentration of 1.005 g/L was determined to be 60.1 ± 0.82 dynes/cm at a temperature of 20.3 ± 0.1 ºC.