Registration Dossier

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Administrative data

Endpoint:
acute toxicity: dermal
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Cross-reference
Reason / purpose:
reference to other study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2000
Report Date:
2000

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: Directive 92/69/EEC Method B3 and OECD Guideline No. 402
Deviations:
no
Test type:
standard acute method
Limit test:
yes

Test material

Reference
Name:
Unnamed
Type:
Constituent

Test animals

Species:
rat
Strain:
Sprague-Dawley
Sex:
male/female

Administration / exposure

Type of coverage:
semiocclusive

Results and discussion

Effect levels
Sex:
male/female
Dose descriptor:
LD50
Effect level:
> 2 000 mg/kg bw
Based on:
test mat.

Any other information on results incl. tables

Table 7.2.2/1: Number of animals dead and number with evident toxicity

Dose
(mg/kg bw)

Conc.
in vehicle

Mortality (# dead/total)

Time range of deaths (hours)

Number with evident toxicity(#/total)

Male

Female

Combined

Male

Female

Combined

2000

500 mg/ml

0

0

0

0

0

0

0

Mean erythema score for all animals:

at 24 hours: 0.7

at 48 hours: 0.4

at 72 hours: 0.2

Mean oedema score for all animals:

at 24 hours: 0.7

at 48 hours: 0

at 72 hours: 0

Applicant's summary and conclusion