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EC number: 202-918-9
CAS number: 101-14-4
For skin irritation one GLP study was available (in vitro test). For eye irritation, one GLP study was available (in vitro test) and some old in vivo data. In order to support the result of the in vivo eye irritation test, QSAR was performed. The substance is not irritating for skin or eye.
MOCA proved to be not irritating in the in
vitro tests for skin and eye irritation, respectively. In an older in
vivo study in rabbits with a mixture of MOCA and related anilines, the
result was also negative. In order to support the result of the in vivo
test, and thus avoid new animal experiments to cover this endpoint,
DEREK calculations were performed for eye irritation. None of the
related anilines, including MOCA, were found to be eye irritants.
to the results of the skin and eye irritation studies, the substance
does not need to be classified according to the
Substance Directive 67/548/EC andCLP
Regulation (EC) 1272/2008.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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