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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to microorganisms

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Administrative data

Link to relevant study record(s)

Description of key information

Toxicity to microorganisms

Key value for chemical safety assessment

EC50 for microorganisms:
100 mg/L
EC10 or NOEC for microorganisms:
100 mg/L

Additional information

Under the conditions of this present test, 4,4’-Methylene bis (2-chloroaniline) was slightly toxic to waste water (activated sludge) bacteria at a loading rate of 100 mg/l (23% inhibition of respiration rate of the sludge). The 3-hour EC50 of 4,4’-Methylene bis (2-chloroaniline) exceeded a loading rate of 100 mg/l.