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EC number: 203-978-9
CAS number: 112-50-5
Diffusion rate determined to be 24 +/-0.9ug/cm2/hr (n=5). (Figure for
reference compound ethylene glycol methyl ether was 2200ug/cm2/hr.)
Damage ratio 1.37 indicating no significant effect on skin barrier
properties following exposure.
An in vitro study determined that the permeability of 2-(2-(2
-ethoxyethoxy)ethoxy)ethanol to human skin is quite low. The
permeability co-efficient was determined to be 24 +/-0.9ug/cm2/hr, which
is around 1% of the skin penetration rate of the shorter chain glycol
ether ethylene glycol methyl ether. Exposure to the substance also
caused no significant deterioration of skin barrier properties.
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