Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 203-978-9 | CAS number: 112-50-5
Partition coefficient
Administrative data
Link to relevant study record(s)
Description of key information
TEGME (measured) :-1.12
TEGBE (measured): 0.56
TEGEE (calculated): -0.96
Key value for chemical safety assessment
- Log Kow (Log Pow):
- -0.6
- at the temperature of:
- 20 °C
Additional information
There is no measured value available for the partition co-efficient of this substance. There is however measured data for two substances either side of it in the homologous series of these triethylene glycol ethers. 2-(2-(2 -methoxyyethoxy)ethoxy)ethanol (TEGME) has a measured value of -1.12 for log kow whereas 2-(2-(2 -butoxyyethoxy)ethoxy)ethanol has a value of 0.51. The value for 2-(2-(2-ethoxyyethoxy)ethoxy)ethanol (TEGEE) will fall somewhere in between. The predicted values for the logkow using the Epiwin QSAR are shown below:
| Substance | Measured logKow | QSAR value |
| TEGME | -1.12 | -1.46 |
| TEGEE | -0.96 | |
| TEGBE | 0.51 | 0.02 |
The QSAR seems to underpredict by a value of about 0.35 to 0.45. A corrected value of around -0.6 is predicted for the logkow and used as the key parameter. A justification for read across/interpolation is attached to chapter 13 of the lead registrant's dossier.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
