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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
activated sludge respiration inhibition testing
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2003
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2003

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test
GLP compliance:
yes (incl. QA statement)

Test material

Reference
Name:
Unnamed
Type:
Constituent

Test organisms

Test organisms (species):
activated sludge
Details on inoculum:
collected from a water treatment works, containing effluent from a predominantly domestic origin.

Study design

Test type:
other: Respiration of activated sewage sludge – 3h static test
Total exposure duration:
3 h
Post exposure observation period:
None.

Test conditions

Hardness:
280 +/- 20 mg/L as CaCO3
Test temperature:
20 to 24 °C
pH:
6.0 to 8.0
Details on test conditions:
- 2 groups containing inoculum at 1.6 mg/L
- 5 test concentrations at 10, 31.6, 100, 316 and 100mg/L and inoculum at 1.6 mg/L
- 3 reference concentrations (3,5-dichlorophenol) at 4, 12 and 36 mg/L and inoculum at 1.6 mg/L
Reference substance (positive control):
yes
Remarks:
3,5-dichlorophenol

Results and discussion

Effect concentrations
Duration:
3 h
Dose descriptor:
EC50
Effect conc.:
> 1 000 mg/L
Nominal / measured:
meas. (geom. mean)
Conc. based on:
test mat.
Basis for effect:
inhibition of total respiration
Remarks:
respiration rate
Results with reference substance (positive control):
3h EC50 for 3,5-dichlorophenol : 13.3 mg/L

Applicant's summary and conclusion

Conclusions:
The 3h EC50 of Thiofestermet on activated sludge is > 1000mg/L. Thiofestermet considered as non-toxic for the micro-organisms of a water treatment plant.