Registration Dossier
Registration Dossier
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EC number: 451-540-2 | CAS number: -
Short-term toxicity to fish
Administrative data
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2003
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 004
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- Version / remarks:
- Directive CEE - Method C1
- GLP compliance:
- yes (incl. QA statement)
Test material
Reference
- Name:
- Unnamed
- Type:
- Constituent
Test organisms
- Test organisms (species):
- Oncorhynchus mykiss (previous name: Salmo gairdneri)
Study design
- Test type:
- semi-static
- Water media type:
- freshwater
- Total exposure duration:
- 96 h
- Remarks on exposure duration:
- solutions changed after 24, 48 and 72h
Test conditions
- Hardness:
- 158 mg CaCO3 / L or 150 +/- 20 mg CaCO3/L
- Test temperature:
- 13.7 to 15.1 °C
- pH:
- 7.72 to 8.13
- Dissolved oxygen:
- 6.5 to 9.3 mg/L (>= 60% of the air saturation value)
- Nominal and measured concentrations:
- Concentration of THIOFESTERMET in the test solutions (mg/L)
See Table below in window "Any other information on materials and methods including tables". - Details on test conditions:
- Mortality and sublethal effects at each concentration recorded at: 0, 2, 4, 24, 48, 72 and 96h.
- Reference substance (positive control):
- no
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 24 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 34.4 mg/L
- Nominal / measured:
- meas. (initial)
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 32.7 mg/L
- Nominal / measured:
- meas. (initial)
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 72 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 32.6 mg/L
- Nominal / measured:
- meas. (initial)
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 33 mg/L
- Nominal / measured:
- meas. (initial)
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Results with reference substance (positive control):
- - Results with reference substance valid? yes
- Mortality: no
- LC100: >= 33.0 mg / l
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- No observed effect after 96 h:>= 33.0 mg/l.
Not classified.
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