Registration Dossier
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EC number: 203-581-0 | CAS number: 108-42-9
Toxicity to terrestrial arthropods
Administrative data
Link to relevant study record(s)
Description of key information
The lethal dose (LD50) of 3-chloroaniline in terrestrial arthropods [Apis mellifera] in a short term study of 48 hrs. on the basis of mortality effect was estimated to be 82.625 µg per animal.
Key value for chemical safety assessment
- Short-term EC50 or LC50 for soil dwelling arthropods:
- 82.625
Additional information
No. of studies were reviewed for toxicity to terrestrial arthropods from reliable sources having Klimisch rating 2 and 4.
The summary of the results are presented below
Sr.No |
Endpoint |
Effect values |
Basis for effects |
Duration |
Species |
Sources |
1 |
LD50 |
82.625 µg per animal |
Mortality |
48 hrs |
Apis mellifera |
Predicted data from QSAR for CAS :108-42-9 |
2 |
EC50 |
10 -30 mg/kg soil dw |
Reproduction |
28 days |
Folsomia candida |
Experimental data from J. Soils Sediments for RA CAS : 95-76-1 |
Based on the studies summarized in the above table for the target substance 3-chloroaniline and the read across substance 3,4-dichloroaniline in terrestrial arthropods (Apis mellifera and Folsomia candida),the endpoint value was found to vary between the lethal dose (LD50) = 82.625 µg per animal and effective concentration (EC50) = 10 -30 mg/kg soil dw in a 48 hrs study to 28 days study on the basis of mortality and reproduction effect.
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