3-chloroaniline

Endpoint summary

Additional information

Biodegradation in water

Based on weight of evidence approach no. of studies were reviewed for biodegradation in water from reliable sources having Klimish rating 2 and 4 for CAS No.:108-42-9

The summary of the results are presented below:

Sr.No	Endpoint	Half-life	Sampling Time	Remark	Conclusion	Sources
1	Biodegradation in water	38 days	-	Readily biodegradable	The half life period of 3-chloroaniline in water is 38 days and based on this value it can be concluded that the chemical is not persistent in water medium since the half life is less than the threshold of 60 days (to qualify the chemical as persistent). Also the diffusion percentage of 3-chloroaniline in water medium is 24%. This coupled with the dilution of water shall result in ready biodegradabililty of the chemical.	Estimated data from PBT Profiler for CAS : 108-42-9
2	Biodegradation in water	-	3 days	Readily biodegradable	In a 3 day cultivation test using 2 different river waters from Japan and two different sea waters, 50% of initial 3-chloroaniline was degraded; the degradation was paralleled by growth of microbes.On this basis, 3-chloroaniline was judged to be readily biodegradable.	Experimental data for CAS :108-42-9
3	Biodegradation in water	-	14 days	Readily biodegradable	In laboratory studies examining the persistence of 3-chloroaniline in water, no significant difference was observed in the degradation rate in pond water, pond water plus sewage sludge inocula, or sterile water over a 14 day period.On this basis, 3-chloroaniline was judged to be readily biodegradable.	Experimental data for CAS :108-42-9

 

Based on the above information,3-chloroaniline was judged to be a readily biodegradable substance.

Biodegradation in water and sediment

Based on weight of evidence approach no. of studies were reviewed for biodegradation in water and sediment from reliable sources having Klimish rating 2 and 4 for CAS No.:108-42-9

The summary of the results are presented below:

Sr.No	Endpoint	Half-life	Remark	Conclusion	Sources
1	Biodegradation in water and sediment	38 days 340 days	Readily biodegradable in water where as it is non biodegradable in sediment.	Half life period of 3-chloroaniline in water is observed to be 38 days (912 hrs ) while in sediment it is 340 days (8160 hrs).Based on these half life values of 3-chloroaniline, it is concluded that the chemical is readily biodegradable in water where as it is non biodegradable in sediment. However, since there is no diffusion of the substance in the sediment medium as evident from the reported data in the table given above and hence persistence in the sediment compartment is not likely to be critical.	Estimated data from PBT Profiler for CAS : 108-42-9
2	Biodegradation in water and sediment	37.5 days 337.5 days	Readily biodegradable in water where as it is non biodegradable in sediment.	Half life period of 3-Chloroaniline in water is observed to be 37.5 days (900 hrs.) while in sediment it is 337.5 days ( 8100 hrs).Based on these half life values of 3-Chloroaniline, it is concluded that the chemical is readily biodegradable in water where as it is non biodegradable in sediment. However, since there is only 0.176 percent diffusion of the substance in the sediment medium as evident from the reported data in the table given above and hence persistence in the sediment compartment is not likely to be critical.	Estimated data from EPI Suite for CAS : 108-42-9
3	Biodegradation in sediment	666.3 days	Non biodegradable in sediment.	A half-life of 666.3 days was observed for 3-chloroaniline incubated under anaerobic conditions with estuarine sediment slurry collected from the Tsurumi River,Japan.On the basis of this half-life value it can be inferred that the substance is persistent in sediment medium and is not readily biodegradable.	Experimental data from publication for CAS : 108-42-9

 

Based on the above information it can be concluded that the substance 3-chloroaniline is considered to be biodegaradable in water medium since the half life does not exceed the threshold of 60 days (to qualify the chemical as persistent) whereas the substance was found to be persistent in sediment medium.

Biodegradation in soil

The PBT Profiler & EPI Suite has estimated that 3-chloroaniline is expected to be found predominantly in soil and its persistence estimate is based on its availability in this medium. Its half-life in soil, 75 days (1800 hrs).,does not exceeds the threshold of 120 days as per Annex XIII of REACH.Therefore, 3-chloroaniline is estimated to be not persistent in the soil environment.

PBT Profiler Estimate

Media	Half-Life (days)	Percent in Medium
Soil	75	76%

Fugacity Model by EPI Suite estimation database

	Mass Amount (percent)	Half-Life (hr)	Emissions (kg/hr)
Soil	75.7	1800	1000

	Fugacity (atm)	Reaction (kg/hr)	Advection (kg/hr)	Reaction (percent)	Advection (percent)
Soil	3.02e-010	802	0	26.7	0