Registration Dossier
Registration Dossier
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EC number: 203-139-7 | CAS number: 103-73-1
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- No information
- Author:
- Bandman A.L. et al.
- Year:
- 1 994
- Bibliographic source:
- VCVGK* "Vrednie chemichescie veshestva, galogen I kislorod sodergashie organicheskie soedinenia"Bandman A.L. et al., Chimia, 1994. Volume(issue)/page/year: -,289,1994
- Reference Type:
- review article or handbook
- Title:
- RTECS Number : BZ8050000
- Author:
- RTECS database
- Year:
- 2 012
- Bibliographic source:
- RTECS (Registry of Toxic Effects of Chemical Substances); VCVGK* "Vrednie chemichescie veshestva, galogen I kislorod sodergashie organicheskie soedinenia"Bandman A.L. et al., Chimia, 1994. Volume(issue)/page/year: -,289,1994
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other:
- Principles of method if other than guideline:
- standard acute method
- GLP compliance:
- not specified
- Test type:
- standard acute method
Test material
- Reference substance name:
- Anisole
- EC Number:
- 202-876-1
- EC Name:
- Anisole
- Cas Number:
- 100-66-3
- Molecular formula:
- C7H8O
- IUPAC Name:
- methoxybenzene
- Details on test material:
- Substance Name: anisole
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- inhalation
- Type of inhalation exposure:
- not specified
- Vehicle:
- not specified
- Duration of exposure:
- 2 h
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LC50
- Effect level:
- 8 949 mg/m³ air
- Based on:
- test mat.
- Exp. duration:
- 2 h
- Remarks on result:
- other: other details not available
- Mortality:
- Lethal concentration, 50 percent kill
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- The 2hr.acute inhalation median lethal concentration (LC50) of anisole in rat was found to be 8949 mg/m3. Acute inhalation toxicity of anisole to rat by inhalative route indicates that the substance does not exhibits acute toxicity by the inhalative route.
- Executive summary:
The 2hr.acute inhalation median lethal concentration (LC50) of anisole in rat was found to be 8949 mg/m3. Acute inhalation toxicity of anisole to rat by inhalative route indicates that the substance does not exhibits acute toxicity by the inhalative route.
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