Phenetole

Ecotoxicological Summary

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:

PNEC aqua (freshwater)

PNEC value:

0.003 mg/L

Assessment factor:

1 000

Extrapolation method:

assessment factor

PNEC freshwater (intermittent releases):

0.027 mg/L

Marine water

Hazard assessment conclusion:

PNEC aqua (marine water)

PNEC value:

0 mg/L

Assessment factor:

10 000

Extrapolation method:

assessment factor

STP

Hazard assessment conclusion:

PNEC STP

PNEC value:

0.533 mg/L

Assessment factor:

10

Extrapolation method:

assessment factor

Sediment (freshwater)

Hazard assessment conclusion:

PNEC sediment (freshwater)

PNEC value:

12.086 mg/kg sediment dw

Extrapolation method:

equilibrium partitioning method

Sediment (marine water)

Hazard assessment conclusion:

PNEC sediment (marine water)

PNEC value:

12.086 mg/kg sediment dw

Extrapolation method:

equilibrium partitioning method

Hazard for air

Air

Hazard assessment conclusion:

no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:

PNEC soil

PNEC value:

5.249 mg/kg soil dw

Extrapolation method:

equilibrium partitioning method

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:

no potential for bioaccumulation

Additional information

Classification is not triggered based on available data, according to REGULATION (EC) No 1272/2008 OF THE EUROPEAN PARLIAMENT AND OF THE COUNCIL on classification, labelling and packaging of substances and mixtures, amending and repealing Directives 67/548/EEC and 1999/45/EC, and amending Regulation (EC) No 1907/2006.

Conclusion on classification

Classification of Phenetole for effects in the environment

Several major guideline – estimation values (Klimisch 2) are available for Phenetole, indicates no toxic effect on fish and other trophic levels.  Thus, the value which have been considered for further calculation (invertebrate) is LC50 = 2.7 mg/L.

 

In determining the classification appropriate to Phenetole, it is necessary to consider all available evidence concerning its persistence, potential to accumulate and predicted or observed environmental fate and behaviour that may present a long-term and/or delayed danger to the structure and/or functioning of aquatic ecosystems. These points are considered below.

 

Persistence

Reliable studies are available to demonstrate that Phenetole is non persistent in nature and so is considered to have rapid biodegradation in the environment. In other words Phenetole degradation may therefore be expected to be fast. Thus it can be inferred that Phenetole is non persistent in character. 

 

Phenetole is non persistent and so do not satisfy the criteria for classification as persistent (P). 

 

Potential to accumulate

Measured log Kow values for Phenetole is less than 4 (Log Kow = 2.041). The potential for Phenetole to bioaccumulate in the tissues of organisms that inhabit aquatic or terrestrial matrices is negligible as the BCF factor for the substance is less than 1000.  

 

 The calculated BCF of Phenetole is 21 dimensionless and below the threshold of 2000. 

 

Phenetole does not satisfy the criterion for classification as bioaccumulative (B).

 

The toxicity values of fish, invertebrates and algae are LC50 = 32.95 mg/L, LC50 = 2.7 mg/L are NOEC = 3.211 mg/L, respectively. The end point result values indicate that the substance will have any effect as the values are within the classifying range. However the data is insufficient for classifying the substance. Thus, considering the CLP Criteria for aquatic classification of the substance and weight of evidence approach , it is concluded that Phenetole does not exhibit toxicity to the aquatic environment and so will not quality as toxic in nature.

So, Phenetole does not satisfies the environmental effects criterion for classification as toxic (T).

 

Thus it can be inferred that Phenetole neither is P & B (including vPvB) substance, nor will qualify as T.