Registration Dossier
Registration Dossier
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EC number: 691-719-4 | CAS number: 1072957-71-1
Biodegradation in soil
Administrative data
Link to relevant study record(s)
Description of key information
An aerobic DT50 value of 509 days was determined in one soil treated with [14C] Phenyl Labelled SYN545192
An aerobic DT50 range of 514 to >1000 days was determined in 5 soils treated with [14C] Pyrazole Labelled SYN545192
An anaerobic DT50 of >1000 days was determined in 1 soil treated with [14C] phenyl and pyrazole labelled SYN545192
An aerobic DT50 range of 162 to 280 days was determined in 3 soils treated with the significant soil metabolite [14C] SYN546206
Key value for chemical safety assessment
- at the temperature of:
- 20 °C
Additional information
Results using phenyl labelled [14C]-SYN545192 demonstrated that the test compound degraded slowly in soil under aerobic conditions (DegT50 of 509 days) to SYN546206, carbon dioxide and other minor components.
Results using pyrazole labelled [14C]-SYN545192 demonstrated that the test compound degraded slowly in soil under aerobic conditions (DegT50 of 514 to >1000 days) to SYN546206, carbon dioxide and other minor components.
Results using phenyl and pyrazole labelled [14C]-SYN545192 demonstrated that the test compound degraded slowly in soil under anaerobic conditions (DegT50 >1000 days) to NOA449410 and other minor components.
Investigation of the rate of degradation of [14C]-SYN546206 was investigated in North Dakota, Gartenacker and 18 Acres soils. The half-lives (DegT50) were 231, 162 and 280 days respectively.
Remark of the registrant: the robust study summaries of the study with metabolite SYN546206 (Ferguson H (2011). Rate of Degradation of 14C-SYN546206 Under Aerobic Conditions in Three Soils at 20°C. Testing laboratory: Syngenta Crop Protection AG. Report no.: 32795. Owner company: Charles River, Tranent, Edinburgh, EH33 2NE, UK. Study number: 218818. Report date: 2012-05-01) is not part of this IUCLID dossier. It is however available on request.
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