Registration Dossier

Environmental fate & pathways

Endpoint summary

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After 28 days, no biodegradation of BPS was reported in a OECD Guideline 301 C test and it did not pass a Japanese MITI ready biodegradability test (0% after 4 weeks).1 2 4

In a Chen et al. study, BPS aerobic degradation was not detected after 2 weeks.3

No data are available for 2,4'-sulfonyldiphenol CAS 5397-34-2.

No data are also available onbenzenesulfonic acid, 4-hydroxy-, sodium salt (1:1), CAS 825-90-1.

From non-standard tests on hydroxybenzenesulphonic acid, it seems likely that hydroxybenzenesulphonic acid is not readily biodegradable.5

On the other hand, the studies with salts of aromatic sulphonic acids called hydrotropes provide a valid read-across.

7 studies on hydrotropes support a conclusion of ready biodegradability.6

A conclusion on DCB 58% can be drawn based on the main component BPS and the similar substances hydrotropes, therefore the intermediate is considered as not readily biodegradable.


1ECHA Registration Dossier BPS CAS 80-09-1;

2SIDS INITIAL ASSESSMENT PROFILE, CAS 80-09-1, CoCAM 4, 16-18 April 2013;

3Min-Yu Chen, Michihiko Ike and Masanori Fujita, Acute toxicity, mutagenicity, and estrogenicity of bisphenol-A and other bisphenols. Environmental Toxicology Volume 17, Issue 1, pages 80–86, 2002;

4EPA, U. S. Environmental Protection Agency, Bisphenol A alternatives in thermal paper, Final Report, January 2014;

5HPV Assessment Report On Hydroxybenzenesulphonic acid CAS No. 1333-39-7, 2004, NOTOX;

6ECHA Registration Dossier, Sodium xylenesulphonate, CAS 1300 -72 -7; ECHA Registration Dossier, Toluene sulphonic acid CAS 104-15-4