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EC number: 606-870-3 | CAS number: 219715-34-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
M-TMP sulfinic acid was tested for its acute toxicity to the rainbow trout (Oncorhynchus mykiss) over a 96-hour exposure period. Results were used to calculate median lethal concentration (LC50) values. No-observed-effect concentrations (NOEC) were also calculated.
The following guidelines were used to conduct this study:
- USEPA FIFRA, 72-1, EPA 540/9-82-024 (1982)
- USEPA TSCA, 40 CFR 797.1400 & 1440 (1992)
- OECD, 203 (1984)
- EEC Directive 92/69/EEC, Part C.1 (1992)
The 96-hour rainbow trout static test was conducted at six treatment levels with nominal concentrations of 3.75, 7.50, 15.0, 30.0, 60.0, and 120 mg/L. A dilution water control was included in the test series. One replicate vessel with five fish was set for each treatment concentration and control for the fish test. The fish were observed daily for sublethal effects (e.g., lethargy, loss of equilibrium) and mortality.
The acute toxicity values for M-TMP Sulfinic Acid with rainbow trout were determined based on nominal concentrations. The resulting values are listed below:
- The 96-hour LC50 value was 92.5 mg/L.
- The 96-hour NOEC was 60.0 mg/L.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 92.5 mg/L
Additional information
The acute toxicity of the test material and water to the Freshwater rainbow trout (Oncorhynchus mykiss) was investigated during a study conducted at The Dow Chemivcal Company. The test was performed from May 22 to 26, 2006 and was conducted according to recognised guidelines and GLP.
This study is presented as the key information as the reliability rating for this study is 2, according to the criteria of Klimisch, 1997, as there was no data reported in this study with regards to analytical monitoring of the test material, this is considered to be a deviation from the guideline and would therefore reduce the reliability.
Based upon the results of the acute fish study, the registered substance meets the following criteria for classification according to: 67/548/EEC: R52/53; Harmful to aquatic organisms, and may cause long-term adverse effects in the aquatic environment.
EC Regulation 1272/2008: Chronic Catergory 3; H412: Harmful to aquatic life with long lasting effects.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.