Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
hydrolysis
Type of information:
(Q)SAR
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with limited documentation / justification
Justification for type of information:
The substance falls outside the applicability domain in view of being a salt, but attempts were made to assess the acid form.
Modelling still failed to provide an adequately viable response
Separate assessment, including use in water-based processes will suggest very slow rate of hydrolysis
Research into sunlight-provked abiotic assessment has been performed (See Section 5.1.3)
Reason / purpose for cross-reference:
reference to other study
Qualifier:
equivalent or similar to guideline
Guideline:
other: Aqueous Base/Acid-Catalyzed Hydrolysis (25 deg C) [HYDROWIN v2.00]:
Principles of method if other than guideline:
The substance is outside the applicabilty domain for modelling
GLP compliance:
no
Specific details on test material used for the study:
The substance falls outside the applicability domain in view of being a salt.
Assessment was also attempted on the acid form, but this too proved unreliable
Radiolabelling:
no
Analytical monitoring:
no
Transformation products:
no
Remarks on result:
hydrolytically stable based on preliminary test
Remarks:
Substance considered stable

Aqueous Base/Acid-Catalyzed Hydrolysis (25 deg C) [HYDROWIN v2.00]:

 Rate constants can NOT be estimated for this structure

Validity criteria fulfilled:
no
Conclusions:
(Q)SAR modelling of the salt or acid form was not possible with an accepteble level of reliability
Substance is conisdered stable in water at environmental pH
The substance is a salt, manufactured by hydrolysing the anhydride starting material in the presence of a base to form a potassium salt.

Description of key information

Hydrolytically stable in the absence of sunlight

The substance is a hydrolysis product of the anhydride.

Key value for chemical safety assessment

Additional information