Registration Dossier

Ecotoxicological information

Toxicity to microorganisms

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

Toxicity to microorganisms: EC50= >100 mg/L; NOEC = 100 mg/L

Key value for chemical safety assessment

EC10 or NOEC for microorganisms:
100 mg/L

Additional information

In a reliable study of the toxicity of trimellitic anhydride to aquatic microorganisms (Lebertz, 1991), the 3 hour EC50, based on inhibition of respiration of activated sludge, was >100, <500 mg TMA-equiv/L. Inhibition, relative to the untreated control, was observed at concentrations >/= 500 mg/L and the NOEC was 100 mg/L.

Rapid hydrolysis of the anhydride to TMLA is presumed to have occurred under the conditions of the test and it is likely that salts were formed by interaction between trimellitic acid and the mineral constituents of the synthetic sewage present in the test system.

No pH measurements were reported; consequently it is uncertain to what degree a lowering of pH may have caused or contributed to the observed effect.