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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Description of key information

Acute toxicity to fish: LC50 = > 792 mg/L; NOEC = 792 mg/L

Key value for chemical safety assessment

EC50/LC50 for freshwater invertebrates:
792 mg/L

Additional information

One reliable study addresses the short-term toxicity of trimellitic anhydride to freshwater invertebrates. In this study (Knacker et al., 1992) TMA was first treated with aqueous NaOH solution, to convert the acid anhydride to the sodium salt(s) of TMLA, and exposure in this study was consequently to sodium trimellitate (following neutralisation of excess alkali).

No toxicity was observed under these conditions: D. magna 48 hour LC50 (static): >792 mg TMA-equiv/L, 96 hour NOEC: 792 mg TMA-equiv/L; These endpoints are mean measured values and represent the highest concentration applied.

Trimellitic anhydride and the more environmentally relevant trimellitic acid (its hydrolysis product) exhibit very low short-term toxicity to aquatic invertebrates.