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Ecotoxicological information

Short-term toxicity to fish

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Description of key information

Acute toxicity to fish: LC50 = > 957 mg/L; NOEC = 957 mg/L

Key value for chemical safety assessment

LC50 for freshwater fish:
957 mg/L

Additional information

One reliable study addresses the short-term toxicity of trimellitic anhydride (TMA) to freshwater fish. In this study (Knacker et al., 1993a) TMA was first treated with aqueous NaOH solution, to convert the acid anhydride to the sodium salt(s) of trimellitic acid (TMLA), and exposure in this study was consequently to sodium trimellitate (following neutralisation of excess alkali).

No toxicity was observed under these conditions: Golden orfe (L. idus melanotus) 96 hour LC50 (static): >957 mg TMA-equiv/L, 96 hour NOEC: 957 mg TMA-equiv/L; These endpoints are mean measured values and represent the highest concentration applied.

Trimellitic anhydride and the more environmentally relevant trimellitic acid (the hydrolysis product of the parent anhydride) exhibit very low short-term toxicity to fish.