Registration Dossier
Registration Dossier
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EC number: 211-711-2 | CAS number: 689-67-8
Sensitisation data (human)
Administrative data
- Endpoint:
- sensitisation data (humans)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Acceptable study report which meets basic scientific principles
Cross-reference
- Reason / purpose for cross-reference:
- reference to same study
Data source
Referenceopen allclose all
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 975
- Reference Type:
- secondary source
- Title:
- Fragrance raw materials monographs
- Author:
- Opdyke DLJ
- Year:
- 1 979
- Bibliographic source:
- Fd. Cosmet. Toxicol., 17 (Suppl.), 787
Materials and methods
- Type of sensitisation studied:
- skin
- Study type:
- study with volunteers
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- Human maximization test
- GLP compliance:
- no
Test material
- Reference substance name:
- 6,10-dimethylundeca-5,9-dien-2-one
- EC Number:
- 211-711-2
- EC Name:
- 6,10-dimethylundeca-5,9-dien-2-one
- Cas Number:
- 689-67-8
- Molecular formula:
- C13H22O
- IUPAC Name:
- 6,10-dimethylundeca-5,9-dien-2-one
Constituent 1
Method
- Type of population:
- general
- Subjects:
- - Number of subjects exposed: 22
- Age: >= 18 - Controls:
- no data
- Route of administration:
- dermal
- Details on study design:
- TYPE OF TEST(S) USED: Maximization test
ADMINISTRATION
- Concentrations: 10%
- vehicle: petrolatum
Results and discussion
- Results of examinations:
- NO. OF PERSONS WITH/OUT REACTIONS COMPARED TO STUDY POPULATION
- Number of subjects with positive reactions: 0/22
- Number of subjects with negative reactions: 22/22
Applicant's summary and conclusion
- Conclusions:
- No sensitizing effects were found, when tested at 10% in human.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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