Registration Dossier
Registration Dossier
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EC number: 221-111-2 | CAS number: 3006-86-8
Endpoint summary
Administrative data
Description of key information
In a weight of evidence approach, the test item is considered to be degradable, but not fullfilling the readily biodegradable criteria.
Additional information
In a modified Sturm Test (Key, 2001) according to OECD 301B, no biodegradation was observed - 5 %.
In a modified Closed Bottle Test (Supporting, 2018) according to OECD 301D, mineralisation of the test item up to 64 % was observed after 114 days of incubation with activated sludge. This test shows that the test item is being consumed to some level after a lag period, which shows that the test item is probably hydrolysed and degraded. Still the obtained mineralisation level is not fulfilling the criteria for ready biodegradability.
In a modified test, microorganisms were exposed to 1,1-di(tert-butylperoxy)cyclohexane in the SCAS test. To this end 1,1-di(tert-butylperoxy)cyclohexane was spiked to the influent of the SCAS test as at a nominal influent concentration of 16 mg/L for a period of 30 weeks. The total removal percentage from the influent measured after ~14 weeks was 98.8%. The removal from the influent through adsorption onto the sludge was only 0.2 – 0.3% and no (significant) removal of the 1,1-di(tert-butylperoxy)cyclohexane by volatilization from the SCAS was measured. A rapid primary biodegradation of 1,1-di(tert-butylperoxy)cyclohexane was demonstrated in the SCAS test, however formation of (bio)degradation products was notdetected. The removal of 1,1-di(tert-butylperoxy)cyclohexane is most likely the result of biodegradation because 1,1-di(tert-butylperoxy)cyclohexane was found stable (persistent) in heat-killed activated sludge. More important the biodegradation of the test substance achieved in the OECD 301D test with pre-exposed (11 weeks and 30 weeks) sludge from the SCAS tests demonstrated the growth linked (ultimate) biodegradation of the 1,1-di(tert-butylperoxy)cyclohexane fraction in the test substance.
In a weight of evidence approach, the test item is considered to be degradable, but not fullfilling the readily biodegradable criteria.
Another prolonged closed bottle test was conducted (AkzoNobel, 2018). Results indicate that the test item probably forms non-extractable residues (NER) and is thus not available for biodegradation.
A sediment simulation test on biodegradation according to OECD 308 with a structural analogue substance (CAS 6731-36-8) has been performed. Please also refer to the read-across justification attached in IUCLID Section 13.
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