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Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
No data
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions
Remarks:
not GLP

Data source

Reference
Reference Type:
publication
Title:
Ergabniss der Untersuchung von 200 chemischen Verbindungen auf akute Fischtoxizitaet mit dem Goldorfentest.
Author:
Juhnke, I., and D. Luedemann
Year:
1978
Bibliographic source:
Z. f. Wasser- und Abwasser-Forsch., 11, 5, 161-164.

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: German guideline "Deutsche Einheitsverfahren zur Wasser-, Abwasser- und Schlamm-Untersuchung, L15: Fischtest (Bestimmung der Wirkung von Wasserinhaltstoffen auf Fische, Vorabdruch in Vom Wasser 46, 291-295 (1976).
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent

Sampling and analysis

Analytical monitoring:
not specified

Test organisms

Test organisms (species):
Leuciscus idus

Study design

Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
48 h

Results and discussion

Effect concentrationsopen allclose all
Duration:
48 h
Dose descriptor:
LC50
Effect conc.:
431.5 mg/L
Nominal / measured:
not specified
Conc. based on:
test mat.
Basis for effect:
mortality
Remarks on result:
other: average of 2 measurements in 2 different labs: 237 and 626 mg/L
Duration:
48 h
Dose descriptor:
LC0
Effect conc.:
329 mg/L
Nominal / measured:
not specified
Conc. based on:
test mat.
Basis for effect:
mortality
Remarks on result:
other: average of 2 measurements in 2 different labs: 200 and 458 mg/L
Duration:
48 h
Dose descriptor:
LC100
Effect conc.:
503 mg/L
Nominal / measured:
not specified
Conc. based on:
test mat.
Remarks on result:
other: average of 2 results in 2 different labs: 273 and 733 mg/L

Any other information on results incl. tables

The results (LC0, LC50 and LC100, respectively) for 2 -methylfuran obtained in the two laboratories are very different:

Effect concentration (48h) Lab 1 Lab 2 Average
LC50 237 626 431.5
LC0 200 458 329
LC100 273 733 503

The average of both laboratories is reported in the Results section.

Applicant's summary and conclusion

Validity criteria fulfilled:
not specified
Conclusions:
The LC50 (48h) values determined in the 2 different laboratories are: 237 and 626 mg/L.
Executive summary:

The short-term toxicity of 2 -methylfuran to fish was assessed according to the German guideline "Deutsche Einheitsverfahren zur  Wasser-, Abwasser- und Schlamm-Untersuchung, L15: Fischtest (Bestimmung  der Wirkung von Wasserinhaltstoffen auf Fische, Vorabdruch in Vom Wasser  46, 291-295 (1976). Fish were exposed for 48h.

The experiment was conducted in 2 different laboratories and both results are reported. The LC50 values (48h) were 237 and 626 mg/L respectively. The LC0 concentrations were 200 and 458 mg/L and the LC100 values reported are 273 and 733 mg/L.