Registration Dossier
Registration Dossier
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EC number: 204-435-9 | CAS number: 120-92-3
Additional information on environmental fate and behaviour
Administrative data
- Endpoint:
- additional information on environmental fate and behaviour
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Good techniques with pure substance.
Data source
Reference
- Reference Type:
- publication
- Title:
- Biotransformation by plant tissue cultures; oxidation-reduction relationship between cycloalkanones and the corresponding cycloalkanols in a cell suspension culture of Nicotiana tabacum.
- Author:
- HAMADA H., KAWABE S., HATANAKA H., MATSUSHIMA H.
- Bibliographic source:
- Okayama Rika Daigaku Kiyo, A19, 75-80
Materials and methods
- Type of study / information:
- The bioconversion of Cyclopentanone to cyclopentanol with the suspension cells of Nicotiana tabacum is an interconvertible oxidoreduction.
Test material
- Reference substance name:
- Cyclopentanone
- EC Number:
- 204-435-9
- EC Name:
- Cyclopentanone
- Cas Number:
- 120-92-3
- Molecular formula:
- C5H8O
- IUPAC Name:
- cyclopentanone
- Details on test material:
- Analytical grade commercial material > 99% pure by GLC.
Constituent 1
Results and discussion
Any other information on results incl. tables
After incubation for 8 days, Cyclopentanone was relatively
unchanged. On the contrary cyclopentanol was quantitatively
converted to Cyclopentanone. The proportion of Cyclopentanone to cyclopentanol in the incubation mixture
became constant with the lapse of the incubation time.
In the time-course experiments starting from equimolecular
mixtures, the proportion converges on the point of about 90%
Cyclopentanone and 10% cyclopentanol.
So it was established that the bioconversion of
Cyclopentanone with the suspension cells of Nicotiana
tabacum is an interconvertible oxidoreduction leading to an
equilibrium. Such an equilibrated interconversion suggests
the participation of a dehydrogenase in the bioconversion of
Cyclopentanone to cyclopentanol.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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