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EC number: 217-568-2
CAS number: 1889-67-4
was applied onto shaved skin of three albino rabbits (New Zealand White)
using semi-occlusive dressings for 4 hours, followed by four
observations at approximately 1, 24, 48 and 72 hours after removal of
the dressings and remaining test substance. The study was performed
according to OECD 404 and Regulation (EC) No 440/2008 Method B.4. Under
the conditions of this study, no skin irritation was caused by
1,1'-(1,1,2,2-tetramethylethylene)dibenzene and no corrosive effect
occurred on the skin in any of the three rabbits. In the area of
application, no staining of the treated skin by
1,1'-(1,1,2,2-tetramethylethylene)dibenzene was observed. No signs of
intoxication were observed during the study period.
1,1'-(1,1,2,2-tetramethylethylene)dibenzene resulted in a primary
irritation index of 0 (erythema and edema score over 24 /48/72 h = 0),
when applied to the intact rabbit skin and is thus classified as not
irritating to the skin.
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