1,2,4-trichlorobenzene

Density

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

density, other

Type of information:

experimental study

Adequacy of study:

weight of evidence

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Justification for type of information:

Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.

Principles of method if other than guideline:

secondary peer reviewed source, valid collection of data

GLP compliance:

not specified

Type of method:

other: no data

Type:

density

Density:

1.46 g/cm³

Temp.:

20 °C

Executive summary:

Roempp, 2009

The density of 1,2,4-Trichlorobenzene was reported as 1.46 g/cm³ at 20 °C.

Reference 2

Endpoint:

density, other

Type of information:

experimental study

Adequacy of study:

weight of evidence

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Justification for type of information:

Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.

Principles of method if other than guideline:

secondary peer reviewed source, valid collection of data

GLP compliance:

not specified

Type of method:

other: no data

Specific details on test material used for the study:

analytical purity: not specified

Type:

density

Density:

1.46 g/cm³

Temp.:

20 °C

Type:

density

Density:

1.36 g/cm³

Temp.:

100 °C

Executive summary:

Rossberg M (Ullmann's Encyclopedia of Industrial Chemistry), 2006

The densitiy of 1,2,4-trichlorobenzenewas reported as 1.456 g/cm³ at 20 °C and 1.358 g/cm³ at 100°C.

Reference 3

Endpoint:

density, other

Type of information:

experimental study

Adequacy of study:

weight of evidence

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Justification for type of information:

Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.

Principles of method if other than guideline:

secondary peer reviewed source, valid collection of data

GLP compliance:

not specified

Type of method:

other: no data

Specific details on test material used for the study:

analytical purity: not specified

Type:

density

Density:

1.46 g/cm³

Temp.:

25 °C

Executive summary:

Lide, 2005

The density of 1,2,4-Trichlorobenzene was reported as 1.46 g/cm³ at 25 °C.

Reference 4

Endpoint:

relative density

Type of information:

experimental study

Adequacy of study:

weight of evidence

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Justification for type of information:

Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.

Principles of method if other than guideline:

secondary peer reviewed source, valid collection of data

GLP compliance:

not specified

Type of method:

other: no data

Specific details on test material used for the study:

analytical purity: not specified

Type:

relative density

Density:

1.46

Temp.:

25 °C

value as cited in the literature: d₂₅²⁵ = 1.4634

Executive summary:

Merck-Index, 2001

The relative density of 1,2,4-Trichlorobenzene was reported as 1.46 at 25 °C.

Reference 5

Endpoint:

density, other

Type of information:

experimental study

Adequacy of study:

weight of evidence

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Justification for type of information:

Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.

Principles of method if other than guideline:

secondary peer reviewed source, valid collection of data

GLP compliance:

not specified

Type of method:

other: no data

Specific details on test material used for the study:

analytical purity: not specified

Type:

density

Density:

1.45 g/cm³

Remarks on result:

other: The temperature was not reported.

value as cited in the literature: liquid density 1.44829 kg/L

Executive summary:

Kirk-Othmer, 2001

The density of 1,2,4-Trichlorobenzene was reported as 1.45 g/cm³.

Reference 6

Endpoint:

density, other

Type of information:

experimental study

Adequacy of study:

weight of evidence

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

other: Original report not available

Justification for type of information:

Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.

Principles of method if other than guideline:

secondary peer reviewed scoure, valid collection af data

GLP compliance:

not specified

Type of method:

other: no data

Specific details on test material used for the study:

analytical purity: not specified

Type:

density

Density:

1.45 g/cm³

Temp.:

20 °C

Executive summary:

Rippen, 1991, Auer, 1988, Dreisbach, 1955, UBA, 1984

The density of 1,2,4-Trichlorobenzene was reported as 1.45 g/cm³ at 20 °C.

Reference 7

Endpoint:

density, other

Type of information:

experimental study

Adequacy of study:

weight of evidence

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

other: Original report not available

Justification for type of information:

Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.

Principles of method if other than guideline:

secondary peer reviewed scoure, valid collection af data

GLP compliance:

not specified

Type of method:

other: no data

Specific details on test material used for the study:

analytical purity: not specified

Type:

density

Density:

1.45 g/cm³

Remarks on result:

other: The temperature was not reported.

1.4542 g/ml

Executive summary:

WHO, 1991

The density of 1,2,4-Trichlorobenzene was reported as 1.45 g/cm³.

Reference 8

Endpoint:

density, other

Type of information:

experimental study

Adequacy of study:

weight of evidence

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

other: Original report not available

Justification for type of information:

Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.

Principles of method if other than guideline:

secondary peer reviewed scoure, valid collection af data

GLP compliance:

not specified

Type of method:

other: no data

Specific details on test material used for the study:

analytical purity: not specified

Type:

density

Density:

1.45 g/cm³

Temp.:

25 °C

Executive summary:

Hooftman, 1982

The density of 1,2,4-Trichlorobenzene was reported as 1.45 g/cm³ at 25 °C.

Reference 9

Endpoint:

density, other

Type of information:

experimental study

Adequacy of study:

weight of evidence

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

other: Original report not available

Justification for type of information:

Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.

Principles of method if other than guideline:

secondary peer reviewed scoure, valid collection af data

GLP compliance:

not specified

Type of method:

other: no ddata

Specific details on test material used for the study:

analytical purity: not specified

Type:

density

Density:

1.46 g/cm³

Temp.:

25 °C

Executive summary:

Ware, 1977

The density of 1,2,4-Trichlorobenzene was reported as 1.46 g/cm³ at 25 °C.

Reference 10

Endpoint:

density, other

Type of information:

experimental study

Adequacy of study:

weight of evidence

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

other: Original report not available

Justification for type of information:

Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.

Principles of method if other than guideline:

secondary peer reviewed scoure, valid collection af data

GLP compliance:

not specified

Type of method:

other: no data

Specific details on test material used for the study:

analytical purity: not specified

Type:

density

Density:

1.44 g/cm³

Temp.:

30 °C

Executive summary:

Dreisbach, 1955

The density of 1,2,4-Trichlorobenzene was reported as 1.44 g/cm³ at 30 °C.

Reference 11

Endpoint:

density, other

Type of information:

experimental study

Adequacy of study:

weight of evidence

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

other: Original report not available

Justification for type of information:

Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.

Principles of method if other than guideline:

secondary peer reviewed scoure, valid collection af data

GLP compliance:

not specified

Type of method:

other: no data

Specific details on test material used for the study:

analytical purity: not specified

Type:

density

Density:

1.46 g/cm³

Temp.:

15 °C

Executive summary:

Kohler, 1954

The density of 1,2,4-Trichlorobenzene was reported as 1.46 g/cm³ at 15 °C.

Reference 12

Endpoint:

density, other

Type of information:

experimental study

Adequacy of study:

weight of evidence

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

other: Original report not available

Justification for type of information:

Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.

Principles of method if other than guideline:

secondary peer reviewed scoure, valid collection af data

GLP compliance:

not specified

Type of method:

other: no data

Specific details on test material used for the study:

analytical purity: not specified

Type:

density

Density:

1.45 g/cm³

Temp.:

25 °C

Executive summary:

Kohler, 1954

The density of 1,2,4-Trichlorobenzene was reported as 1.45 g/cm³ at 25 °C.

Reference 13

Endpoint:

density, other

Type of information:

experimental study

Adequacy of study:

weight of evidence

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

other: Original report not available

Justification for type of information:

Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.

Principles of method if other than guideline:

secondary peer reviewed scoure, valid collection af data

GLP compliance:

not specified

Type of method:

other: no data

Specific details on test material used for the study:

analytical purity: not specified

Type:

density

Density:

1.47 g/cm³

Temp.:

10 °C

Executive summary:

Jungfleisch, 1868

The density of 1,2,4-Trichlorobenzene was reported as 1.47 g/cm³ at 10 °C.

Reference 14

Endpoint:

density, other

Type of information:

experimental study

Adequacy of study:

weight of evidence

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

other: Original report not available

Justification for type of information:

Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.

Principles of method if other than guideline:

secondary peer reviewed scoure, valid collection af data

GLP compliance:

not specified

Type of method:

other: no data

Specific details on test material used for the study:

analytical purity: not specified

Type:

density

Density:

1.45 g/cm³

Temp.:

26 °C

Executive summary:

Jungfleisch, 1868

The density of 1,2,4-Trichlorobenzene was reported as 1.45 g/cm³ at 26 °C.

Reference 15

Endpoint:

density, other

Type of information:

experimental study

Adequacy of study:

weight of evidence

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

other: Original report not available

Justification for type of information:

Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.

Principles of method if other than guideline:

secondary peer reviewed scoure, valid collection af data

GLP compliance:

not specified

Type of method:

other: no data

Specific details on test material used for the study:

analytical purity: not specified

Type:

density

Density:

1.41 g/cm³

Temp.:

56 °C

Executive summary:

Jungfleisch, 1868

The density of 1,2,4-Trichlorobenzene was reported as 1.41 g/cm³ at 56 °C.

Reference 16

Endpoint:

density, other

Type of information:

experimental study

Adequacy of study:

weight of evidence

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

other: Original report not available

Justification for type of information:

Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.

Principles of method if other than guideline:

secondary peer reviewed scoure, valid collection af data

GLP compliance:

not specified

Type of method:

other: no data

Specific details on test material used for the study:

analytical purity: not specified

Type:

density

Density:

1.24 g/cm³

Temp.:

196 °C

Executive summary:

Jungfleisch, 1868

The density of 1,2,4-Trichlorobenzene was reported as 1.24 g/cm³ at 196 °C.

Description of key information

The individual study reports (data from handbooks or collection of data) show some deficiencies with respect to the comprehensiveness of the experimental details. Therefore, a reliability of 1 or 2 and thus adequacy as key study was not assignable for any of the individual studies. Consequently, the studies were assigned a Klimisch score of 4 (according to guidance document R.4, ‘not assignable: studies or data […] which are only listed in short abstracts or secondary literature (books, reviews, etc.)). As the individual studies report values are in a similar range, collectively, these studies can be used to conclude on this endpoint and to satisfy the information requirement.

 

The density of 1,2,4-trichlorobenzene was determined in a series of experimental studies and is 1.45 g/cm³ to 1.46 g/cm³ in the temperature range from 20 °C to 25 °C.
The experiments by Jungfleisch show a decrease in density with an increase in temperature (10 °C - 196 °C; 1.47 g/cm³ - 1.24 g/cm³). The density of 1.46 g/cm³ (determined at room temperature: 20-25 °C) was chosen as key value for chemical safety assessment.

Roempp, 2009
The density of 1,2,4-Trichlorobenzene was reported as 1.46 g/cm³ at 20 °C.

Rossberg M (Ullmann's Encyclopedia of Industrial Chemistry), 2006
The densitiy of 1,2,4-trichlorobenzenewas reported as 1.456 g/cm3 at 20 °C and 1.358 g/cm3 at 100°C.

Lide, 2005
The density of 1,2,4-Trichlorobenzene was reported as 1.46 g/cm³ at 25 °C.

 

Merck-Index, 2001 

The relative density of 1,2,4-Trichlorobenzene was reported as 1.46 at 25 °C.

Kirk-Othmer, 2001
The density of 1,2,4-Trichlorobenzene was reported as 1.45 g/cm³.

Rippen, 1991, Auer, 1988, Dreisbach, 1955, UBA, 1984
The density of 1,2,4-Trichlorobenzene was reported as 1.45 g/cm³ at 20 °C.

WHO, 1991
The density of 1,2,4-Trichlorobenzene was reported as 1.45 g/cm³.

Hooftman, 1982
The density of 1,2,4-Trichlorobenzene was reported as 1.45 g/cm³ at 25 °C.

Ware, 1977
The density of 1,2,4-Trichlorobenzene was reported as 1.46 g/cm³ at 25 °C.

Dreisbach, 1955
The density of 1,2,4-Trichlorobenzene was reported as 1.44 g/cm³ at 30 °C.

Kohler, 1954
The density of 1,2,4-Trichlorobenzene was reported as 1.46 g/cm³ at 15 °C.

Kohler, 1954
The density of 1,2,4-Trichlorobenzene was reported as 1.45 g/cm³ at 25 °C.

Jungfleisch, 1868
The density of 1,2,4-Trichlorobenzene was reported as 1.47 g/cm³ at 10 °C.

Jungfleisch, 1868
The density of 1,2,4-Trichlorobenzene was reported as 1.45 g/cm³ at 26 °C.

Jungfleisch, 1868
The density of 1,2,4-Trichlorobenzene was reported as 1.41 g/cm³ at 56 °C.

Jungfleisch, 1868
The density of 1,2,4-Trichlorobenzene was reported as 1.24 g/cm³ at 196 °C.

Key value for chemical safety assessment

Relative density at 20C:

1.46

Additional information

unit: g/cm³