1-Propanol, 2-methyl-3-[(1,7,7-trimethylbicyclo[2.2.1]hept-2-yl)oxy]-

Hydrolysis

Description of key information

In the hydrolysis test (equivalent to OECD TG 111) in test 1, Bornafix was found to undergo significant hydrolysis at 50°C at pH 4 (41.5%), pH 7 (40.8%) and pH 9 (39.5%) over a period of five days. According to the test method it can be estimated that 50% hydrolysis occurring in 2.4 hours at 50°C is equivalent to a half-life time of 1 day at 25°C and 10% hydrolysis occurring in 5 days at 50°C is equivalent to a half-life time of 1 year at 25°C. Applying these criteria to the results obtained for Bornafix in test 1, the half-life time at 25°C can be estimated to be between 1 day and 1 year at pH 4, 7 and 9. In test 1, the hydrolysis reaction was shown to be pseudo first order at pH 4, 7 and 9, requiring test 3 to be performed to determine the half-life times. Test 3 was performed at 25°C, (determinations at 60 and 70°C were aborted due to loss of test compound through evaporation), and at the 97-day analysis point a dramatic slowing/halt in the hydrolysis reaction was observed. Graphical representation of the data produced non-linear plots. Measurement or estimation of the half-life time, as stated in the Directive, from the non-linear plots has not been possible because of the uncertainty of the rate of reaction. Therefore the disappearance of the substance may also be due to e.g. evaporation, this is because the chemical structure of the substance has no hydrolysable groups: the ether and the alcohol substructures are unlikely to hydrolyse.

Key value for chemical safety assessment

Half-life for hydrolysis:

1 yr

at the temperature of:

25 °C