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Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
4 (not assignable)

Data source

Reference
Reference Type:
other: Body responsible for the test
Title:
Unnamed
Year:
1992

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: Annex V, B1 bis
GLP compliance:
yes
Test type:
fixed dose procedure
Limit test:
yes

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid: particulate/powder
Remarks:
migrated information: powder

Test animals

Species:
rat
Strain:
Wistar
Sex:
male/female

Administration / exposure

Route of administration:
oral: unspecified
Vehicle:
corn oil
Doses:
Main : 2000 mg/kg
No. of animals per sex per dose:
Preliminary sighting study: 0 (male)
Preliminary sighting study: 1 (female)

Main study: 5 male
Main study: 5 female

Results and discussion

Effect levels
Sex:
male/female
Dose descriptor:
discriminating dose
Effect level:
2 000 mg/kg bw
Mortality:
no mortality
Clinical signs:
none of the animals died. Signs of slight but not evident toxicity, including diarhoea, piloerection and upward curve of the spine, with complete recovery by day 7.

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information