Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 239-635-5 | CAS number: 15578-26-4
Genetic toxicity: in vitro
Administrative data
- Endpoint:
- in vitro gene mutation study in bacteria
- Type of information:
- (Q)SAR
- Remarks:
- VEGA model: CONSENSUS 1.0.2; CAESAR 2.1.13; SarPy/IRFMN 1.0.7; ISS 1.0.2
- Adequacy of study:
- key study
- Study period:
- 2018
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model, but not (completely) falling into its applicability domain, and documentation / justification is limited
- Justification for type of information:
- VEGA model - CONSENSUS 1.0.2 (CAESAR 2.1.13; SarPy/IRFMN 1.0.7; ISS 1.0.2)
Data source
Reference
- Reference Type:
- other: QSAR model
- Title:
- Mutagenit (Amest test) CONSENSUS 1.0.2 (CAESAR 2.1.13; SarPy/IRFMN 1.0.7; ISS 1.0.2) - VEGA
- Year:
- 2 018
- Bibliographic source:
- VEGA QSAR model - Mutagenit (Amest test) CONSENSUS 1.0.2 (CAESAR 2.1.13; SarPy/IRFMN 1.0.7; ISS 1.0.2)
- Report date:
- 2018
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- VEGA model - CONSENSUS 1.0.2 (CAESAR 2.1.13; SarPy/IRFMN 1.0.7; ISS 1.0.2)
Test material
- Reference substance name:
- Ditin pyrophosphate
- EC Number:
- 239-635-5
- EC Name:
- Ditin pyrophosphate
- Cas Number:
- 15578-26-4
- Molecular formula:
- H4O7P2.2Sn
- IUPAC Name:
- ditin pyrophosphate
- Test material form:
- solid: particulate/powder
Constituent 1
Results and discussion
Test results
- Key result
- Species / strain:
- not specified
- Metabolic activation:
- not applicable
- Genotoxicity:
- other:
- Cytotoxicity / choice of top concentrations:
- other:
- Remarks on result:
- no mutagenic potential (based on QSAR/QSPR prediction)
Applicant's summary and conclusion
- Conclusions:
- Tin(II) pyrophosphate is not classified for genetic toxicity
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
