Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
skin sensitisation, other
Remarks:
in silico
Type of information:
(Q)SAR
Remarks:
VEGA model - Skin sensitization (CAESAR) 2.1.6
Adequacy of study:
key study
Study period:
2018
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model, but not (completely) falling into its applicability domain, and documentation / justification is limited
Justification for type of information:
VEGA model - Skin sensitization (CAESAR) 2.1.6

Data source

Reference
Reference Type:
other: QSAR model
Title:
Skin sensitization (CAESAR) 2.1.6 - VEGA
Year:
2018
Bibliographic source:
VEGA QSAR model - Skin sensitization (CAESAR) 2.1.6
Report date:
2018

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
VEGA model - Skin sensitization (CAESAR) 2.1.6

Test material

Constituent 1
Chemical structure
Reference substance name:
Ditin pyrophosphate
EC Number:
239-635-5
EC Name:
Ditin pyrophosphate
Cas Number:
15578-26-4
Molecular formula:
H4O7P2.2Sn
IUPAC Name:
ditin pyrophosphate
Test material form:
solid: particulate/powder

Results and discussion

In vitro / in chemico

Results
Key result
Parameter:
other: QSAR model
Remarks on result:
no indication of skin sensitisation

Applicant's summary and conclusion

Conclusions:
Tin(II) pyrophosphate is not classified for skin sensitisation according to Regulation (EC) n. 1272/2008