Registration Dossier

Ecotoxicological information

Short-term toxicity to fish

Currently viewing:

Administrative data

Link to relevant study record(s)

Referenceopen allclose all

Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 203 (Fish, Acute Toxicity Test)
Deviations:
no
GLP compliance:
yes
Analytical monitoring:
no
Test organisms (species):
Oncorhynchus mykiss (previous name: Salmo gairdneri)
Test type:
semi-static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
96 h
Test temperature:
13 ± 1°C
pH:
8.0
Nominal and measured concentrations:
Nominal concentrations of 0.46, 1.0, 2.2, 4.6 and 10 mglL
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
3.2 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality
Conclusions:
Exposure to the test item gave LC50 (96 h) 3.2 mg/L.
Executive summary:

A study was performed to assess the acute toxicity of Lakeland ACP 70 to rainbow trout (Oncorhynchus mykiss) under semi-static conditions. The study was conducted in accordance with the EEC Methods for Determination of Ecotoxicity Annex to Directive 92/69/EEC (OJ. No. L383A, 29.12.92) Part C, Method 1 "Acute toxicity for Fish" and the OECD Guideline for Testing of Chemicals No. 203 "Fish, Acute Toxicity Test". Groups of seven juvenile fish were exposed to a range of concentrations of Lakeland ACP 70 dispersed in water. Observations were made on the numbers of dead fish and the incidence of sublethal effects after 3, 6, 24, 48, 72 and 96 hours exposure. Results were reported as LC50 (96 h) 3.2 mg/L.

Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 203 (Fish, Acute Toxicity Test)
Deviations:
no
GLP compliance:
yes
Analytical monitoring:
no
Test organisms (species):
other: Scophthalmus maximus
Test type:
semi-static
Water media type:
saltwater
Remarks:
artifical seawater
Limit test:
no
Total exposure duration:
96 h
Test temperature:
15.5 ± 1.5°C.
pH:
- Mean pH 7.70 to 7.86 during definitive study
Nominal and measured concentrations:
Nominal concentrations of 1.0, 1.78, 3.16, 5.62 and 10.0 mg/L test item
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
3.6 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality
Conclusions:
Exposure of juvenile turbot to the test item gave LC50 (96 h) 3.6 mg/L.
Executive summary:

A sample of ACP 70 was assessed for its potential toxicity to juvenile turbot in a semi-static test over 96 hours in accordance with the PARCOM method 1995, OECD guideline 203. Nominal test concentrations of ACP 70 were prepared over the range of 1.0 mg 1-1 to 10.0 mg 1-1. Juvenile turbot were exposed to the test concentrations in order to determine the concentration which killed 50% of the test organisms over 96 hours (LC50). Results were reported as LC50 (96 h) 3.6 mg/L.

Description of key information

Results are available for one species of freshwater fish and one species of marine fish.

Key value for chemical safety assessment

LC50 for freshwater fish:
3.2 mg/L
LC50 for marine water fish:
3.6 mg/L

Additional information