Registration Dossier

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

This Chemical Safety Report characterizes the hazards and risks associated with the use of NPEO, a non-ionic surfactant belonging to a larger group of compounds called alkylphenol ethoxylates (APEs).

Data for the UVCB NPEO is available for certain but not all environmental fate endpoints. To address the remaining information requirements, results from other nonylphenol (NP) homologues was used. These include:

  • Nonylphenol (NP)

  • Nonylphenol 1 ethoxylate (NPE-1)

  • Nonylphenol 1.5 ethoxylate (NPE-1.5)

  • Nonylphenol 2 ethoxylate (NPE-2) and

  • Nonylphenol 9 ethoxylate (NPE-4)

The use of data on NPE homologues with various degrees of ethoxylation to assess the environmental hazard of NPEO is justified due to their structural similarities, common functional groups and comparable degradation pathway. Also, there areincremental and constant change across the homologues relating to the physical-chemical, environmental fate, ecotoxicological and toxicological properties.

A more detailed read-across justification is attached to Chapter 13 of the IUCLID file.