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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Long-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Description of key information

The NOEC, LOEC and MATC for this study are 0.551, 0.930 and 0.716 mg/L. Recalculated NOEC = 0.16 mg/L.

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
0.16 mg/L

Additional information

The study by Marino et al., (2003) was carried out in accordance with GLP and recognised test guidelines. The NOEC, LOEC and MATC reported in this study are 0.551, 0.930 and 0.716 mg/L.This result was not based on the Time Weighted Average, recommended in the OECD test guidelines, and therefore the NOEC has been recalculated, using the raw data provided in the report to give a NOEC of 0.16 mg/L. A notable restriction of this study is that the experimenters had difficulty in maintaining the concentration of test substance during the exposure period due in part to the physical and chemical properties of vinyl acetate, and also likely due to a build up of biomass and/or polymerised test material. This has been taken into account when scoring the reliability of this study and assessing whether it can be used.