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EC number: 203-545-4
CAS number: 108-05-4
were derived for freshwater, saltwater, sediment, and soil using either
experimental results or equilibrium partitioning calculations. The PNECS
derived using experimental data were based on Klimisch 1 or 2 studies
because these studies took into account the physico-chemical properties
of vinyl acetate and therefore were conducted in closed systems with no
or minimal headspace to avoid loss of the test material and ensure a
consistent exposure of the organisms. Other studies were available but
did not meet the quality criteria and therefore these were not used in
the PNEC derivation.
(based on the ecosar class vinyl/allyl esters) were generated using EPI
suite, in order to support the use of lower assessment factors for
derivation of the PNECs. The QSARs generated reinforce that fish are the
most sensitive trophic level.
Based on the criteria of
Regulation (EC) No 1272/2008, vinyl acetate has to be classified as “Chronic
aquatic toxicity, category 3”, hazard statement H412 “Harmful
to aquatic life with long-lasting effects".
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