Registration Dossier
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EC number: 273-227-8 | CAS number: 68953-84-4
Sediment toxicity
Administrative data
Link to relevant study record(s)
Description of key information
1) Key: Sediment-Water Chironomid Toxicity test using spiked sediment; OECD 218; GLP; K1; 28 days; no effects observed at any of the tested concentrations.
Key value for chemical safety assessment
- EC10, LC10 or NOEC for freshwater sediment:
- 615.25 mg/kg sediment dw
Additional information
Toxicity towards sediment organisms was evaluated in this GLP compliant OECD218 (Sediment-Water Chironomid Toxicity used spiked sediment) study. The organims (Chironomus riparius) were exposed to a control, solvent control, 25, 64, 160, 400 and 1000 mg DAPD/kg dry sediment (nominal). The test chemical was added once at the beginning of the study.
These nominal concentrations corresponded to respectively 0, 0, 6.8, 30.2, 84.4, 255.5 and 615. 3 mg test chemical/kg dry sediment (Days 0 & 28 - average, measured). Recovery of the measured levels of DAPD in sediment ranged from 27 -63% whereas there was no measured levels of the chemical in overlying water at Day 28 in any of the test concentrations. The average number of emerging midges at the respective concentrations were: 16.2, 14.7, 13.5, 14, 15.7, 14, 14. These results indicated that no effects could be observed in any of the concentrations. In addition, there was no impact of the test substance on develomental rates of the organisms. Therefore the NOEC (28 days) both for emergence and development rate is 1000 mg DAPD/kg dry sediment (nominal) or 615.25 mg DAPD/kg dry sediment (measured).Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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