Registration Dossier
Registration Dossier
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EC number: 248-273-7 | CAS number: 27157-94-4
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- activated sludge respiration inhibition testing
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2013
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Reason / purpose for cross-reference:
- reference to same study
- Qualifier:
- according to guideline
- Guideline:
- other: OECD Guideline 301 D (Ready biodegradability: Closed Bottle Test)
- GLP compliance:
- yes
- Test organisms (species):
- sewage, domestic
- Details on inoculum:
- Secondary effluent from a municipal wastewater treatment plant in Usserød, Denmark, wihich predominantly receives domestic sewage.
- Total exposure duration:
- 28 d
- Reference substance (positive control):
- yes
- Remarks:
- Benzoic acid, sodium salt
- Duration:
- 28 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 2.4 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- inhibition of total respiration
- Duration:
- 28 d
- Dose descriptor:
- EC0
- Effect conc.:
- 2.4 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- inhibition of total respiration
- Duration:
- 28 d
- Dose descriptor:
- other: Oxygen consumption
- Effect conc.:
- 31.9 other: % of ThOD
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- other: Oxygen concentration
- Basis for effect:
- inhibition of total respiration
- Validity criteria fulfilled:
- not applicable
- Conclusions:
- The oxygen consumption corresponded to 36.6% of the ThOD after 14 days in the toxicity control. Therefore the test item can be considered not inhibitory to the inoculum according to this test guideline.
- Executive summary:
In biodegradation test OECD 301 D was followed under GLP compliance. The oxygen consumption corresponded to 36.6% of the ThOD after 14 days in the toxicity control. Therefore the test item can be considered not inhibitory to the inoculum according to this test guideline.
Reference
Description of key information
In biodegradation test OECD 301 D was followed under GLP compliance. The oxygen consumption corresponded to 36.6% of the ThOD after 14 days in the toxicity control. Therefore the test item can be considered not inhibitory to the inoculum according to this test guideline.
Key value for chemical safety assessment
- EC10 or NOEC for microorganisms:
- 2.4 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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