Registration Dossier
Registration Dossier
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EC number: 500-044-5 | CAS number: 25791-96-2 1 - 6.5 moles propoxylated
Endpoint summary
Administrative data
Description of key information
Not irritating to skin or eye.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Additional information
Skin Irritation study was performed in accordance to OECD 404. Very slight erythema (grade 1) was observed in one animal only at the 1 hour observation period. All test sites appeared normal at 24 hours. Propoxylated glycerol mw 300 is not a skin irritant according EU criteria following a 4 hour occlusive exposure to rabbit skin. Classification: not irritating.
Eye Irritation study was performed in accordance to OECD 405. Conjuctival redness (grade 2) was observed in the eye of 2 rabbits at 1 hour post-instillation. Residual test material was observed around the treated eye of all rabbits 1 hour after treatment. All irritation fully reversed within 24 hours after dosing.
Propoxylated glycerol mw 300 was not an eye irritant according to EC criteria.
Justification for classification or non-classification
Findings of testing do not warrant classification according to EU GHS.
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