Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 239-685-8 | CAS number: 15602-15-0
Endpoint summary
Administrative data
Description of key information
Skin irritation:
Corrosive or irritating to the skin (OECD 439; GLP). Since the RhE test methods covered by OECD TG 439 cannot resolve between UN GHS Categories 1 or 2, a follow-up study will be conducted to distinguish between the two categories and upon study completion, a robust study summary will be incorporated in the REACH registration dossier.
Eye irritation:
According to the bovine corneal opacity and permeability assay, no prediction can be made, since the IVIS score was between 3 and 55 (OECD 437; GLP). However, the in vitro skin irritation test (OECD 439; GLP) showed a mean relative tissue viability of 2.9 % (clear positive finding indicating possible corrosive properties). Since the eye is the more susceptible tissue, it is assumed as a worst-case scenario that magnesium 2-ethylhexanoate should be classified as inducing irreversible effects on the eye (Category 1; H318).
Key value for chemical safety assessment
Additional information
Justification for classification or non-classification
Skin irritation:
The substance was observed to be either corrosive or irritating to the skin in a reliable in vitro skin irritation/corrosion study according to OECD 439. Since the RhE test methods covered by OECD TG 439 cannot resolve between UN GHS Categories 1 or 2, no hazard conclusion can be made due to lack of data on corrosive/irritating properties.
Eye irritation:
According to the bovine corneal opacity and permeability assay, no prediction can be made, since the IVIS score was between 3 and 55 (OECD 437; GLP). However, the in vitro skin irritation test (OECD 439; GLP) showed a mean relative tissue viability of 2.9 % (clear positive finding indicating possible corrosive properties). Since the eye is the more susceptible tissue, it is assumed as a worst-case scenario that magnesium 2-ethylhexanoate should be classified as inducing irreversible effects on the eye (Category 1; H318).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
